Wednesday, March 31, 2010

Another Dietary Connection to Fertility: Fish Oil

Add another notch to the belt of fish oil purveyors. A study recently published in Human Reproduction found that diets high in omega-3 fatty acids were less likely to develop endometriosis.

Endometriosis is a common, painful, and very demoralizing female medical condition. Long before it causes infertility in many patients, the "stray" endometrial tissue that is the hallmark of the disease makes everyday life a cycle-related struggle. Very painful periods are a common sign of endometriosis, and unfortunately, the related complaints of many teens and young women are dismissed.

Untreated endometriosis can continue undiagnosed for years until a woman finds out as a result of infertility. Accurate diagnosis is only accomplished with diagnostic laparoscopy. Many times during that diagnostic procedure itself, treatment can also be performed, in the form of removing the endometrial growths.

Research to learn more about the beginnings of endometriosis is ongoing. With this new information about links between diet and the disease's occurrence, women may be able to take a more active role in preventing this and other potential debilitating conditions.

Monday, March 1, 2010

Is Ovarian Transplant For Real?

The journal Human Reproduction reported last week on a Danish woman who has now become pregnant and given birth twice as a result of one ovarian tissue transplant procedure.

Ovarian tissue transplant is one of the most experimental methods for rescuing a woman's fertility prior to her undergoing sterility-causing treatment for cancer. The more usual ways to "set aside" a woman's fertility for later use are to freeze either embryos or egg cells.

Dr. Stinne Holm Bergholdt, 32, had cortical tissue from her one ovary removed and cryopreserved before going through chemotherapy for bone cancer. She survived cancer and used the frozen tissue, after transplanting it on to her existing ovary, to successfully conceive first one child (in 2007) and then another in 2009.

There have been only a few successful pregnancies resulting from ovarian transplant, and most of those have been among women who were twins. Being twins removes much of the tissue rejection risk inherent in the transplantation of any organ. Anti-rejection medications are required for tissue transplant procedures, though patients should be informed that they don't provide guarantees of success and aren't covered by insurance.

The thing that makes Dr. Berholdt's case newsworthy is that she's the first to have a second pregnancy with the same tissue, and spontaneously (that is, without medical assistance.)

Without much larger numbers of ovarian transplant patients to observe, it's nearly impossible to derive much from Dr. Bergholdt's story that would be of value to most infertility patients. There are so many variables of fertility for each individual person, it's simply impossible to gauge why this one was so successful.

The plausability of using transplanted ovarian tissue for most women is still an unanswered question.